Table 1.

A summary of the behavioural results from rats and mice subjected to chronic and acute footshock or restraint and i.c.v. administration of CRF in the Porsolt forced swim test (rats and mice), and in the tail-suspension test (mice only). The arrows indicate the direction of the changes; parentheses indicate that the trends were not statistically significant. In most cases the results were obtained from multiple experiments. For full details see Swiergiel et al. (1997ab), and Dunn and Swiergiel (2008), from which this table is derived.

Mouse Forced Swim Test
Acute Treatment	None	Acute Footshock	Acute Restraint	Icv CRF
Chronic Treatment
None		(↓)	↓	↓
Chronic Footshock	↑	↓	↓	0
Chronic Restraint		nd		nd
Mouse Tail Suspension Test
Acute Treatment	None	Acute Footshock	Acute Restraint	Icv CRF
Chronic Treatment
None		↓	↓	↓
Chronic Footshock	(↓)	(↓)	0	0
Chronic Restraint	↓	nd	↓	nd
Rat Forced Swim Test
Acute Treatment	None	Acute Footshock	Acute Restraint	Icv CRF
Chronic Treatment
None		↓	↓	↑
Chronic Footshock	↑	↓	0	0
Chronic Restraint	(↓)	nd	↓	nd