Table 1.

GO annotation analysis

Upregulation			Downregulation
Changed	P Value	GO Term	Changed	P Value	GO Term
10	0.00003	RNA processing	6	0.00000	extracellular structure organization and biogenesis
4	0.00045	female pregnancy	11	0.00004	cell adhesion
3	0.00054	spliceosome assembly	6	0.00012	skeletal development
3	0.00059	protein homo-oligomerization	3	0.00016	synapse organization and biogenesis
4	0.00092	negative regulation of signal transduction	4	0.00032	phosphate transport
4	0.00115	protein-RNA complex assembly	2	0.00042	cell aging
3	0.00117	cellular component disassembly	3	0.00056	regulation of cyclin-dependent protein kinase activity
2	0.00247	fibroblast growth factor receptor signaling pathway	2	0.00083	cartilage condensation
2	0.00506	protein amino acid acetylation	2	0.00201	regulation of ossification, bone mineral formation
1	0.00536	endochondral ossification	4	0.00201	inorganic anion transport
2	0.00725	viral genome replication	2	0.00279	regulation of bone remodeling
4	0.00794	ribonucleoprotein complex biogenesis and assembly	3	0.00459	oxygen and reactive oxygen species metabolic process
8	0.01163	immune response	2	0.00623	cartilage development
2	0.01504	positive regulation of caspase activity	4	0.00629	negative regulation of cell proliferation
1	0.01601	virus-infected cell apoptosis	2	0.01862	fatty acid biosynthetic process
2	0.01759	mitochondrion organization and biogenesis	2	0.02424	response to oxidative stress
24	0.03018	nucleobase nucleoside nucleotide and nucleic acid metabolic process	2	0.02885	female pregnancy
2	0.03863	positive regulation of hydrolase activity	3	0.03374	negative regulation of progression through cell cycle
13	0.04665	cell differentiation	3	0.04077	neuron differentiation
1	0.04727	regulation of protein binding	3	0.04290	regulation of transferase activity
2	0.04747	regulation of cellular component organization and biogenesis	5	0.04322	regulation of cell cycle
3	0.04886	antiapoptosis	3	0.04344	positive regulation of cell proliferation

GO, gene ontology.