Table 1. WNK 1 single nucleotide polymorphisms.
tSNP | gene positiona | Chr12 nt position (bp) | Alleles | MAFb | HWE p Controls | |
1 | rs7137188 | 5′ | 724592 | C/T | 0.48 | 0.1 |
2 | rs1468326 | 5′ | 727762 | C/A | 0.11 | 0.8 |
3 | rs3088353 | 5′ | 732901 | A/C | 0.46 | 0.9 |
4 | rs11064519 | i1 | 741472 | C/G | 0.34 | 0.0001 |
5 | rs2369402 | i1 | 748925 | G/A | 0.21 | 0.1 |
6 | rs2107612 | i1 | 758581 | A/G | 0.27 | 0.7 |
7 | rs2107613 | i1 | 758689 | C/T | 0.23 | 0.4 |
8 | rs11608756 | i1 | 760094 | A/G | 0.39 | 0.04 |
9 | rs11064524 | i1 | 760163 | G/T | 0.25 | 0.8 |
10 | rs11064527 | i1 | 761286 | A/C | 0.16 | 0.4 |
11 | rs11064536 | i1 | 775843 | T/C | 0.17 | 0.5 |
12 | rs765250 | i1 | 778544 | A/G | 0.31 | 0.5 |
13 | rs12314329 | i1 | 779992 | A/G | 0.08 | 0.4 |
14 | rs11611246 | i4 | 809741 | G/T | 0.22 | 0.3 |
15 | rs6489756 | i4 | 834767 | A/G | 0.47 | 0.7 |
16 | rs12816718 | i6 | 840061 | G/T | 0.15 | 0.6 |
17 | rs2286007 | ex8 | 841552 | C/T | 0.07 | 0.7 |
18 | rs11611231 | i8 | 844587 | C/G | 0.10 | 0.4 |
19 | rs4980973 | i9 | 853307 | A/G | 0.13 | 0.0002 |
20 | rs4980974 | i9 | 855289 | A/G | 0.44 | 0.6 |
21 | rs880054 | i10 | 858819 | A/G | 0.41 | 1 |
22 | rs956868 | ex13 | 861173 | A/C | 0.14 | 0.4 |
23 | rs953361 | i22 | 872068 | C/T | 0.40 | 0.7 |
24 | rs2301880 | i23 | 874098 | C/T | 0.24 | 0.7 |
25 | rs2286026 | i26 | 885434 | A/G | 0.41 | 0.9 |
26 | rs2286028 | i26 | 885730 | C/G | 0.20 | 0.7 |
27 | rs2277869 | I26 | 887171 | C/T | 0.16 | 1 |
28 | rs11571461 | 3′ | 896580 | A/G | 0.07 | 0.3 |
i: intron, e: exon, 5′: 5 prime; 3′: 3 prime.
Minor allele frequency.