TABLE 1.
Characteristics of non-Hispanic Caucasian C282Y homozygotes and control participants
| Characteristics |
C282Y homozygotes |
Control participants (n=364) | ||
|---|---|---|---|---|
| Previously-diagnosed (n=87) |
Newly diagnosed |
|||
| Ferritin elevated* (n=131) | Ferritin not elevated† (n=64) | |||
| Age, years | 57.4±13.5 | 51.7±13.6 | 45.7±10.3 | 56.3±14.1 |
| Age range, years, n (%) | ||||
| 24 to 44 | 14 (16) | 40 (30) | 27 (42) | 75 (21) |
| 45 to 64 | 47 (54) | 65 (50) | 36 (56) | 180 (49) |
| 65 and older | 26 (30) | 26 (20) | 1 (2) | 109 (30) |
| Women, n (%) | 39 (45) | 67 (51) | 55 (86) | 222 (61) |
| Transferrin saturation, % | 63.4±25.9 | 75.6±20.4 | 51.0±27.1 | 28.5±9.1 |
| Serum ferritin, μg/L‡ | 186.0 (58.0, 470.0) | 616.0 (428.0, 911.0) | 90.0 (32.0, 132.0) | 84.0 (50.5, 138.0) |
Data presented as mean ± SD, unless otherwise indicated.
*
Serum ferritin >200 μg/L for women, >300 μg/L for men;
†
Serum ferritin ≤ 200 μg/L for women, ≤ 300 μg/L for men;
‡
Serum ferritin results presented as median (25th percentile, 75th percentile)