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. Author manuscript; available in PMC: 2009 May 15.
Published in final edited form as: Bioorg Med Chem Lett. 2008 Jan 8;18(10):3047–3051. doi: 10.1016/j.bmcl.2008.01.003

Table 2.

Representative 2-PCPA derivatives synthesized and kinetically evaluated for LSD1, MAOA, and MAOB inhibition

graphic file with name nihms52901t2.jpg
Compound R1 R2
7 Ph Ph
8 1-naphthyl H
9 4-CF3C6H4 H
10 4-BrC6H4 H
11 4-CH3OC6H4 H
12 3-thienyl H