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. 2009 Apr 7;4(4):e5021. doi: 10.1371/journal.pone.0005021

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Eme et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Conservation of functional domains composition among mammalian components, and their orthologues in fungi (A. fumigatus, Neurospora crassa, Cryptococcus neoformans, Ustilago maydis, Schizosaccharomyces pombe and S. cerevisiae), amoebozoa (D. discoideum and E. histolytica), green plants and algae (A. thaliana, Oryza sativa and Ostreococcus tauri), alveolates (Paramecium tetraurelia Cryptosporidium hominis, Plasmodium falciparum, and Theileria annulata), heterokonts (P. ramorum and T. pseudonana) and excavates (T. brucei, Leishmania major, G. lamblia and Trichomonas vaginalis). Orthologues in these 21 non-animal species having identical functional domains composition to their mammalian counterparts are represented by blue bars, whereas those having a different functional domain composition are represented by red bars.