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. 2009 Apr 7;4(4):e5021. doi: 10.1371/journal.pone.0005021

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Eme et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Pink sections represent proteins composed only of eukaryotic-specific functional domains (i.e. they have no homologues in prokaryotes, meaning that they probably appeared after the divergence of eukaryotes and prokaryotes); green sections represent proteins exclusively composed of domains shared by prokaryotes and eukaryotes (i.e. suggesting that these domains may have a more ancient origin since they may have arisen before eukaryotic divergence); yellow sections represent proteins composed by a combination of both types of domains. (A) Domain composition of 152 components of the mammalian midbody having detectable functional domains. The three remaining proteins have no functional domain detected above threshold. (B) Domain composition of 88 components inferred to be present in LECA having detectable functional domains. (C) Domain composition of the 64 Unikont-specific components.