TABLE 2.

Evidence for linkage in regions previously reported to harbor IDDM loci

Locus	Chromosome	Defined by marker(s)	Marker tested	LOD	P
IDDM1	6p21.3	HLA-DQβ1	rs1019937	213.2	8.0 × 10−216
IDDM2	11p15.5	INS-VNTR	rs1004446	3.09	0.00008
IDDM3	15q26	D15S107	rs906310	0.00	0.6
IDDM4	11q13	D11S1917	rs923346	0.87	0.02
IDDM5	6q25	ESR	rs11902	0.00	0.5
IDDM6	18q	D18S64	rs1943418	0.68	0.04
IDDM7	2q31	D2S152	rs696092	1.91	0.002
IDDM8	6q27	D6S264	rs6910121	0.45	0.07
IDDM9	3q21-25	D3S1303	rs1983380	0.40	0.09
IDDM10	10cen	D10S193	rs959629	1.07	0.013
IDDM11	14q24.3	D14S67	rs1012921	0.13	0.2
IDDM12	2q33	CTLA4	rs1947983	1.05	0.014
IDDM13	2q34	IGFBP2	rs1851328	0.63	0.04
IDDM15	6q	D6S283	rs2207958	5.99*	7.5 × 10−8
IDDM16	14q32.3	D14S293	rs872945	0.05	0.3
IDDM17	10q25	D10S592	rs151603	0.16	0.2
IDDM18	5q33-34	IL12B	rs270664	0.01	0.4
	1q42	D1S1617	rs342817	0.00	0.5
	16q22-24	D16S3098	rs1037973	1.24	0.008

*Not corrected for allele sharing at IDDM1. Adjustment based upon the expected LOD at D6S283 and the recombination fraction with HLA yields an adjusted LOD of 2.7.