Figure 1.

Schematic diagram showing the diffraction data characteristics as a function of resolution. The data completeness drops off sharply beyond 2.5 Å as a result of radiation decay, but the higher-resolution reflections are still useful as indicated by the signal-to-noise ratio. In total 18,805 reflections were measured, yielding 11,373 unique observations between 41.0 and 2.3 Å. The overall multiplicity-weighted R_merge (43) is 13.1%, increasing to 48.5% in the highest-resolution shell.