Table 1. MicroRNAs significantly altered in NPC tissues.

		Mean expressiona			P-value
MicroRNA	Chromosome	Normal	NPC	Fold change	T-test	Mann–Whitney
U-regulated
miR-196b	7p15	4.04	6.75	6.54	1.45E−04	2.68E−03
miR-138	3p21, 16q13	4.58	7.27	6.45	7.77E−04	4.04E−03
miR-155	21q21	7.50	10.09	6.04	2.05E−05	1.75E−03
miR-142-3p	17q22	9.43	11.73	4.92	6.95E−04	1.75E−03
miR-18a	13q31	5.20	7.50	4.92	6.00E−05	1.75E−03
miR-25a	7q22	7.22	9.28	4.18	3.43E−05	1.75E−03
miR-205	1q32	16.01	18.02	4.00	1.51E−03	4.04E−03
miR-106a	Xq26	9.25	11.18	3.80	2.37E−04	4.04E−03
miR-17	13q31	10.67	12.41	3.34	2.08E−03	8.81E−03
miR-15ba	3q26	4.68	6.39	3.27	2.38E−04	1.75E−03
miR-17a	13q31	5.15	6.84	3.22	4.40E−04	1.75E−03
Downregulated
miR-204	9q21	10.37	4.91	−44.15	3.51E−07	1.75E−03
miR-449a	5q11	8.54	4.42	−17.45	4.28E−05	2.68E−03
miR-34c-3p	11q23	11.92	8.15	−13.64	1.55E−03	6.01E−03
miR-187	18q12	10.23	6.80	−10.74	1.26E−04	1.75E−03
miR-145	5q33	16.77	13.39	−10.42	7.03E−05	1.75E−03
miR-143	5q33	12.50	9.17	−10.07	2.89E−05	1.75E−03
miR-34c-5p	11q23	9.30	6.04	−9.63	2.49E−03	8.81E−03
miR-34b	11q23	8.36	5.37	−7.92	5.74E−03	8.81E−03
miR-100	11q24	12.93	10.05	−7.36	6.79E−04	1.75E−03
miR-9	1q22, 5q14, 15q26	7.16	4.34	−7.07	7.34E−05	1.75E−03
miR-139-5p	11q13	11.59	8.83	−6.75	1.18E−06	1.75E−03
miR-195	17p13	9.98	7.26	−6.61	9.96E−05	1.75E−03
miR-148a	7p15	8.13	5.46	−6.36	2.33E−04	2.68E−03
miR-30aa	6q13	10.08	7.50	−5.99	2.10E−03	8.81E−03
miR-497	17p13	12.12	9.63	−5.62	1.64E−04	2.68E−03
miR-135a	3p21, 12q23	7.88	5.71	−4.49	3.63E−03	4.04E−03
miR-130a	11q12	9.94	7.84	−4.29	2.77E−04	2.68E−03
miR-31	9p21	12.53	10.51	−4.05	1.50E−03	6.01E−03
miR-199b-5p	9q34	7.67	5.74	−3.83	2.05E−03	6.01E−03
miR-200a	1p36	7.32	5.59	−3.32	1.87E−03	4.04E−03
miR-29c	1q32	7.78	6.09	−3.25	2.53E−03	1.27E−02
miR-152	17q21	10.30	8.65	−3.13	1.04E−03	6.01E−03
miR-200b	1p36	12.01	10.36	−3.13	1.59E−03	1.75E−03
miR-532-3p	Xp11	13.52	11.92	−3.03	4.10E−03	8.81E−03

^aMean expression levels expressed as 39 – C_t.