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. 2009 Feb 24;100(6):932–940. doi: 10.1038/sj.bjc.6604938

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Copyright © 2009 Cancer Research UK

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Proliferation and clonogenic assays of RT- and RT+P529-treated cells. (A) Administration of 2 Gy to PC-3 cells causes a 30% cell growth inhibition, whereas addition of P529 to 2 Gy radiation results in 85% cell growth inhibition (P<0.001). P529 also enhances the antiproliferative effect of 4 Gy radiation (P<0.05). (B) In clonogenic assays, P529 enhances the effect of RT with significant differences between RT and RT+P529, when 2 and 4 Gy are administered to the cells (P<0.05, and P<0.01, respectively). ^*P<0.05; ^**P<0.01; ^***P<0.001.