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. 2009 Feb 24;100(6):932–940. doi: 10.1038/sj.bjc.6604938

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Copyright © 2009 Cancer Research UK

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Effect of P529, ionising radiation, and the combination of both treatments on Id-1, VEGF, MMP-9, and MMP-2 protein levels. Amount of Id-1 is increased by RT, but addition of P529 reduces Id-1 below control levels. The combination RT+P529 also decreases RT-induced VEGF levels. Active MMP-9 is reduced in RT-treated cells by the addition of P529. Levels of active MMP-2 are also decreased by the addition of P529 to RT-treated cells. In the densitometric analysis, the Y-axis represents fold changes with respect to control.