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. 2009 Feb 24;100(6):932–940. doi: 10.1038/sj.bjc.6604938

Table 1. Cell growth inhibition 50 (GI50) of P529 in the NCI-60 tumor cell lines panel.

Panel/cell line GI50 (μM)
Leukemia
 CCRF-CEM  
 HL-60(TB) 2.28
 K-562 4.11
 MOLT-4 32.7
 RPMI-8226 21.5
 SR 2.14
   
Non-small cell lung cancer
 A549/ATCC 13.1
 EKVX 22.3
 HOP-62 11.2
 NCI-H226 21.2
 NCI-H23 15.1
 NCI-H322M 34.3
 NCI-H460 11.4
 NCI-H522 8.84
   
Colon cancer
 COLO 205 23.7
 HCC-2998 12.1
 HCT-116 10.8
 HCT-15 12.9
 HT29 6.04
 KM12 14.2
 SW-620 14.5
   
CNS cancer
 SF-268 6.09
 SF-295 12.2
 SF-539 14.7
 SNB-19 11.2
 SNB-75 5.18
 U251 12
   
Melanoma
 LOX IMVI 22.5
 MALME-3M 17.2
 M14 16.4
 SK-MEL-2 18.6
 SK-MEL-26 14.5
 SK-MEL-5 9.12
 UACC-257 15.4
 UACC-62 12.1
   
Ovarian cancer
 ICROV1 14.9
 OVCAR-3 12.8
 OVCAR-4 12.8
 OVCAR-5 24.1
 OVCAR-8 9.02
 SK-OV-3 13.6
   
Renal cancer
 786-0 16.2
 A496 15.9
 ACHN 13.3
 CAKI-1 11.2
 RXF 393 5.24
 SN 12C 17
 TK-10 18.2
 UO-31 15.5
   
Prostate cancer
 PC-3 12.4
 DU-145 18.6
   
Breast cancer
 MCF7 6.01
 NCI/ADR-RES 12.6
 MDA-MB-231/ATCC 14.7
 HS 578T 13.3
 MDA-MB-435 2.64
 BT-549 17