GSK inhibitors slow ATP consumption. Panel A, mitochondria were de-energized with dinitrophenol for 5 minutes, in Panel B, mitochondria were treated with cyanide for 20 minutes, and in Panel C, mitochondria were anoxic for 60 minutes. Both GSK inhibitors significantly decrease the rate of ATP hydrolysis. Results are Means ± SEM (n=6). *p<0.05 vs. control.