Table 3.
Multigender, multisite, and multispecies tumorigens in ToxRefDB.
| Rat
|
Mouse
|
Rat
|
Mouse
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Chemical | Multigender | Multisite | Multigender | Multisite | Multispecies | Chemical | Multigender | Multisite | Multigender | Multisite | Multispecies |
| Carbaryl | 2 | 2 | 1 | 1 | 2 | Tribufos | 3 | 4 | |||
| Dipropyl isocinchomeronate | 1 | 1 | 1 | 1 | 1 | Amitraz | 3 | 3 | |||
| Fenoxycarb | 3 | 3 | |||||||||
| Fentin | 5 | 5 | 4 | 4 | Spiroxamine | 3 | 3 | ||||
| Dazomet | 5 | 5 | 3 | 4 | Tefluthrin | 3 | 3 | ||||
| Clodinafop-propargyl | 4 | 4 | 4 | 4 | Permethrin | 2 | 2 | ||||
| Lactofen | 3 | 3 | 5 | 4 | Trifloxystrobin | 2 | 2 | ||||
| Dimethoate | 5 | 4 | 4 | 4 | Chloridazon | 1 | 1 | ||||
| Malathion | 4 | 4 | 1 | 1 | Triforine | 1 | 1 | ||||
| Diuron | 4 | 3 | 1 | 1 | Dichlorvos | 5 | 5 | N | N | N | |
| Dacthal | 2 | 2 | 1 | 1 | Pyraclostrobin | 5 | 5 | N | N | N | |
| Isoxaflutole | 2 | 2 | 1 | 1 | Alachlor | 4 | 3 | N | N | N | |
| Spirodiclofen | 2 | 2 | 1 | 1 | Captan | N | N | 3 | 3 | N | |
| Diclofop-methyl | 4 | 4 | 4 | Maneb | N | N | 2 | 2 | N | ||
| Cinmethylin | 3 | 3 | 3 | Azafenidin | 4 | ||||||
| Imazalil | 3 | 3 | 3 | Lindane | 4 | ||||||
| Nitrapyrin | 3 | 3 | 3 | Fluazinam | 3 | ||||||
| Propoxur | 2 | 2 | 2 | Paclobutrazol | 3 | ||||||
| Daminozide | 2 | 1 | 2 | Acephate | 2 | ||||||
| Thiacloprid | 4 | 4 | 1 | Linuron | 2 | ||||||
| Vinclozolin | 3 | 4 | 1 | Propanil | 2 | ||||||
| Di(2-ethylhexyl)phthalate | 1 | 1 | 1 | Triasulfuron | 1 | ||||||
| Folpet | 5 | 1 | 1 | Fipronil | 4 | ||||||
| MGK (octacide 264) | 2 | 1 | 1 | Thiabendazole | 3 | ||||||
| Iprodione | 1 | 1 | 1 | Boscalid | 2 | ||||||
| Cacodylic acid | 5 | 3 | Pendimethalin | 2 | |||||||
| Propyzamide | 4 | 3 | Pyrimethanil | 2 | |||||||
| Oxadiazon | 5 | 3 | 5,5-Dimethylhydantoin | 1 | |||||||
| Resmethrin | 2 | 2 | Cyazofamid | 1 | |||||||
| Pyrithiobac-sodium | 1 | 2 | Chloropicrin | 5 | |||||||
| Bentazone | 2 | 2 | Fenamiphos | 5 | |||||||
| Fluthiacet-methyl | 5 | 2 | Molinate | 5 | |||||||
| Metaldehyde | 2 | 2 | Chlorpyrifos-methyl | 4 | |||||||
| Triflusulfuron-methyl | 2 | 2 | Fluoxastrobin | 1 | |||||||
| Fludioxonil | 2 | 2 | Fenitrothion | 5 | |||||||
| Prodiamine | 1 | 1 | Cyproconazole | 4 | |||||||
| Tepraloxydim | 2 | 1 | Prochloraz | 4 | |||||||
| Clofencet-potassium | 1 | 1 | Thiamethoxam | 3 | |||||||
| Isoxaben | 1 | 1 | Bispyribac-sodium | 2 | |||||||
| Pymetrozine | 1 | 1 | Piperonyl butoxide | 2 | |||||||
| Topramezone | 1 | 1 | Propiconazole | 2 | |||||||
| Triadimefon | 1 | 1 | Acifluorfen-sodium | 1 | |||||||
| Oryzalin | 4 | 4 | Difenoconazole | 1 | |||||||
| Simazine | 4 | 4 | Primisulfuron-methyl | 1 | |||||||
| Tebufenpyrad | 4 | 4 | Pyraflufen-ethyl | 1 | |||||||
| Dichloran | 3 | 3 | Thiodicarb | 1 | |||||||
| Dimethenamid | 3 | 3 | Fenoxaprop-ethyl | 4 | |||||||
| Prosulfuron | 3 | 3 | Buprofezin | 2 | |||||||
| Acetochlor | 3 | 2 | Propargite | 4 | N | N | N | ||||
| Ametryn | 2 | 3 | Dichlobenil | 2 | N | N | N | ||||
| Oxytetracycline HCl | 1 | 1 | Quintozene | 2 | N | N | N | ||||
| Bifenthrin | 5 | 5 | Tralkoxydim | 3 | N | N | N | ||||
| Disulfoton | 5 | 5 | Benomyl | N | N | 3 | N | ||||
| Metam-sodium | 4 | 5 | Cloprop | N | N | 2 | N | ||||
| Quizalofop-ethyl | 4 | 4 | Thiophanate-methyl | N | N | 1 | N | ||||
Relative potency: 5, ≤ 15 mg/kg/day; 4, ≤ 50 mg/kg/day; 3, ≤ 150 mg/kg/day; 2, ≤ 500 mg/kg/day; 1, > 500 mg/kg/day; N, not assessed (no study available).