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. 2009 Mar 31;7(3):e1000072. doi: 10.1371/journal.pbio.1000072

Figure 6. ATP-Dependent Processive Motility Is a Property of Dimeric but Not Monomeric KIF1A Motors.

Figure 6

In vitro single-molecule motility assays of dimeric (1–393)-3xmCit or monomeric (1–369)-3xmCit KIF1A were carried out. Analysis includes motile events lasting at least 0.3 s. (A) Representative kymographs.

(B) Distribution of velocities.

(C) Distribution of run lengths.

(D and E) Comparison of motile properties of monomeric and dimeric motors in the presence of ATP or ADP. Distribution of velocities (D) or run lengths (E) for KIF1A(1–393), (1–369), or KHC(1–891) in the presence of ATP or ADP as a function of time spent in one-directional motility. Red ovals, 1D diffusion. Blue ovals, processive motility.