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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Mol Cell Neurosci. 2008 Sep 18;40(1):39–49. doi: 10.1016/j.mcn.2008.08.011

Fig. 6. Protein expression levels of cell adhesion molecules NCAM and N-cadherin are upregulated in SK2-/- mice.

Fig. 6

A: Western blot analysis reveals that at 6 weeks of age, a time at which approximately 40% of OC fibers remain and are still actively degenerating, NCAM expression is significantly upregulated by approximately 50% over the level of the wild type age-matched control (p=0.0171). At 15 weeks, a time at which degenerative processes are complete, NCAM expression appears slightly lower that wild type age-matched samples, but no statistically significant difference was detected. Histogram is relevant for the 140kDa NCAM isoform (the major isoform expressed in the cochlear lysate).