Table 1.
Maternal characteristics and obstetrical history
| Paroxetinen = 463 | Fluoxetinen = 346 | Controln = 1467 | P-value | |
|---|---|---|---|---|
| Maternal age (years) median (IQR) | 32* (28–36) | 32* (28–36) | 31 (27–34) | <0.001 |
| Gravidity (%) | ||||
| 1 | 119/417 (28.5) | 89/312 (28.5) | 384/1411 (27.2) | 0.812 |
| 2–4 | 233/417 (55.9) | 167/312* (53.5) | 846/1411 (60.0) | 0.063 |
| ≥5 | 65/417 (15.6) | 56/312* (17.9) | 181/1411 (12.8) | 0.040 |
| Parity (%) | ||||
| 0 | 143/423 (33.8) | 110/315 (34.9) | 474/1410 (33.6) | 0.907 |
| 1–3 | 250/423 (59.1) | 177/315 (56.2) | 850/1410 (60.3) | 0.403 |
| ≥4 | 30/423 (7.1) | 28/315 (8.9) | 86/1410 (6.1) | 0.189 |
| Previous miscarriage (%) | ||||
| 0 | 332/416 (79.8) | 255/305 (83.6) | 1135/1402 (81.0) | 0.423 |
| 1 | 58/416 (13.9) | 30/305 (9.8) | 194/1402 (13.8) | 0.159 |
| ≥2 | 26/416 (6.3) | 20/305 (6.6) | 73/1402 (5.2) | 0.530 |
| Previous ETOP ≥1 (%) | 50/416 (12.0) | 55/308* (17.9) | 126/1402 (9.0) | <0.001 |
| Previous stillbirth ≥1 (%) | 5/415 (1.2) | 2/303 (0.7) | 12/1401 (0.9) | 0.719 |
| Gestational age at initial contact median (IQR) | 8* (6–13) | 8* (6–13) | 9 (7–15) | <0.001 |
| Cigarette smoking (%) | ||||
| Nonsmokers | 295/372* (79.3) | 234/293* (79.9) | 978/1057 (92.5) | <0.001 |
| <10 cig day−1 | 25/372* (6.7) | 23/293* (7.8) | 33/1057 (3.1) | <0.001 |
| ≥10 cig day−1 | 52/372* (14.0) | 36/293* (12.3) | 46/1057 (4.4) | <0.001 |
*
P < 0.05 exposed vs. controls. ETOP, elective termination of pregnancy; IQR, interquartile range.