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. 2008 Oct 31;283(44):29802–29811. doi: 10.1074/jbc.M800494200

FIGURE 6.

FIGURE 6.

A and B, oral lipid tolerance test in rats. The study was conducted as described under “Experimental Procedures.” The time course (A) and area under the curve (AUC)(B) of the initial 6 h of TAG detected in the serum was plotted. For each group, n = 6. Data shown are means ± S.E. *, p < 0.05 as compared with vehicle control. C, gastric emptying assay in rats. The study was conducted as detailed under “Experimental Procedures.” XP620 at 10 and 30 mg/kg did not affect gastric emptying, whereas 5 μg of CCK-8 significantly reduced emptying of the test meal. For each group, n = 10. Data shown are means ± S.E. **, p < 0.01 as compared with vehicle control. D, MTP in vitro assay. Data shown are means ± S.D. of triplicate determinations.