TABLE 2.
t½
|
|||||||
---|---|---|---|---|---|---|---|
2% DMSO | 0.1 μm Compound III | 10 μm Compound III | 100 μm Compound III | ||||
min | |||||||
Redox free | 145 ± 2 | 137 ± 7 | 142 ± 2 | 122 ± 9 | |||
GSH | 1525 ± 44 | 1715 ± 18 | 1214 ± 225 | 1343 ± 49 | |||
β-ME | 1693 ± 53 | 1673 ± 12 | 1639 ± 51 | 1762 ± 130 | |||
l-Cystine | 1697 ± 35 | 1663 ± 85 | 1623 ± 16 | 1557 ± 99 | |||
Lipoic acid | 1193 ± 222 | 1489 ± 31 | 1168 ± 47 | 633 ± 101 | |||
Dihydrolipoic acid | 167 ± 5 | 1.3 ± 0.1 | NDa | ND | |||
DTT | 1191 ± 60 | 4.1 ± 0.2 | ND | ND |
ND, not determined