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. 2008 Nov 7;283(45):30557–30565. doi: 10.1074/jbc.M801877200

FIGURE 2.

FIGURE 2.

Effect of deglycosylation on the 18.5- and 17-kDa PrPSc fragments. Immunoblot analyses of frontal cortex homogenates from MM1, MM2C, and VV1 subtypes are shown. PK-treated samples were either untreated or treated with PNGase F and probed with SAF60. The 18.5-and 17-kDa fragments are marked with filled and empty arrowheads, respectively. The same result was reproduced twice with samples from at least three subjects for each group. Approximate molecular masses are in kilodaltons.