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Schematic representations of Pax-8 PAI subdomain. Panel a shows the hydrogen bonds found between the Leu37 carbonyl oxygen and Gln40 side chain and backbone amide nitrogens (Nε-2 and HN). Panel b depicts the hydrophobic residue side chains around Leu62 (in cyan), i.e. 5 Å apart. The cluster is an important part of the hydrophobic core of the PAI subdomain.
