FIGURE 6.
Mapping of the results of the saturation transfer experiments on the modeled structure of MGL1. A-C correspond to Fig. 5, A-C. The residues with reduction ratios of more than 0.3, 0.15-0.3, and 0.1-0.15 are colored red, orange, and yellow, respectively. Residues without available data (prolines, Glu-22, Asn-70, Asn-87, His-99, and Met-131) are colored cyan. D, surface representation of the modeled structure of MGL1. The residues identified as the LewisX binding site on MGL1 are mapped on the surface of the modeled structure of MGL1. The colors are used in the same scheme as in A. The residues colored red, orange, and yellow form a contiguous face on MGL1.