Table 1. Baseline characteristics in the four arms.

	SP	CD	SP+AQ	AQ+AS
Number	28	81	80	83
Median age in years (IQR)	21 (19–26)	21 (19–27)	20 (19–25)	21 (19–26)
Median gestation in months (IQR)	6 (5–8)	7 (6–8)	7 (5–7)	6 (5–7)
Mean haemoglobin g/dL (SD)	9.3 (1.3)	9.6 (1.2)	9.0 (1.3)	9.3 (1.3)
Median parasite count (/200 WBC)	184 (55–535)	106 (23–650)	25 (51–578)	181 (62–628)
Median days unwell	3	3	3	3
% with primary education	93	90	85	91
Gametocytes at presentation (%)	23%	20%	17%	12%
DHFR triple mutation; N = 131* (51I+59R+108N)	83.3% (10/12)	94.7% (36/38)	100% (46/46)	97.1% (34/35)
DHPS double mutation; N = 137 (S436+437G+540E)	92.3% (12/13)	89.2% (33/37)	97.9% (46/47)	85.0% (34/40)
DHFR Triple+DHPS double; N = 119	81.8% (9/11)	82.4% (28/34)	97.7% (42/42)	93.5% (29/31)
HIV test positive (%)	0/27	1/80 (1.3)	1/82 (1.2)	0/79
Primiparous** (%)	7/12 (58)	26/42 (62)	14/38 (39)	20/34 (59)

^*Some samples for PCR were lost in transit from field to laboratory.

^**Parity was not recorded for the initial study participants.