Table 1.
GR and MR mRNA in the dentate gyrus in ADX corticosterone-implanted rats treated with either l-NAME or daily injections of additional cortocosterone or both
Treatment (in addition to ADX + 30% corticosterone pellet s.c.) | Optical density (pixels) |
|
---|---|---|
GR mRNA | MR mRNA | |
Oil s.c. + saline i.p. | 112.6 ± 3.05 | 304.9 ± 32.57 |
Oil s.c. + l-NAME (50 mg/kg) | 113.4 ± 2.60 | 244.2 ± 28.60 |
Daily cort (2 mg/kg) + saline i.p. | 126.0 ± 2.36 | 277.7 ± 21.93 |
Daily cort (2 mg/kg) + l-NAME (50 mg/kg) | 119.2±1.65 | 233.6±10.15 |
Data are presented as mean ± SD; Significance levels: Pairwise comparisons (Bonferroni): *P < 0.05, **P < 0.01 compared to control group.