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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Pharmacol Biochem Behav. 2008 Sep 5;91(3):436–440. doi: 10.1016/j.pbb.2008.08.022

Fig. 1.

Fig. 1

Time course of the antinociceptive effect of nociceptin (NOC, panel A) or noiceptin1–13 amide (NOC-NH2, panel B) after spinal administration. Doses were 1–100 nmol/frog for nociceptin and 10–100 nmol/frog for noiceptin1–13 amide. N=6–8 animals per treatment dose and saline-injected controls.