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. 2009 Mar 23;119(4):899–910. doi: 10.1172/JCI37771

Figure 5. Keratinocyte differentiation is impaired in Srf mutant epidermis.

Figure 5

(A and B) Immunohistochemical analysis of tail-skin sections from control and Srf mutant mice (P11–P15) for the expression of epidermal differentiation markers. (A) Expression of K14, K15, and K5 was reduced and their localization was irregular in Srf mutant tail skin. Expression of the differentiation markers K10 and loricrin was delayed and reduced compared with that in control skin. (B) Srf mutant mice show abnormal interfollicular expression of K6, K17, and K8/K18. Sections were counterstained with hematoxylin. Scale bar: 100 μm.