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. Author manuscript; available in PMC: 2009 Mar 30.
Published in final edited form as: Expert Opin Med Diagn. 2008 Sep 1;2(9):1055–1065. doi: 10.1517/17530050802361161

Table 2.

Comparison of MRI, optical coherence tomography (OCT) and coherent anti-Stokes Raman scattering (CARS).

MRI OCT CARS microscopy
Contrast mechanisms 1H nuclei magnetic resonance Backreflection of photons C–H vibration
Resolution
Lateral 0.1~1 mm 15 ~20 μm ~0.3 μm
Axial 1 ~ 3 mm 3 ~ 10 μm ~ 0.7 μm
Penetration depth Whole brain 1 ~3 mm ~ 100 μm
Imaging speed 10 min ~ 1 h 200 ms 50 ms ~ 1 s
Field of view 4 ~ 28 cm 6 mm 200 ~ 700 μm
Current applications MS patients Eyes in MS patients Tissue and animal

MS: Multiple sclerosis.