Table 3.
Subject characteristics for the placebo‐controlled trial of salsalate at maximum tolerated dose (mean ± SD).
| Salsalate | Placebo | p‐value | |
|---|---|---|---|
| Age (year) | 51 ± 12 | 54 ± 8 | 0.6 |
| Gender | 3 M, 5 F | 5 M, 4 F | 0.5 |
| BMI (kg/m2) | 32.5 ± 6.4 | 31.5 ± 4.9 | 0.7 |
| FBS (mmol/L) | 7.5 ± 1.0 | 7.0 ± 1.4 | 0.4 |
| HbA1c (%) | 7.1 ± 1.2 | 6.7 ± 0.5 | 0.3 |
| SBP (mm Hg) | 125 ± 12 | 132 ± 15 | 0.3 |
| DBP (mm Hg) | 71 ± 4 | 78 ± 10 | 0.1 |
| Chol (mmol/L) | 3.9 ± 0.8 | 4.7 ± 0.7 | 0.04 |
| Treatment | 5 Met, 1 SFU, 2 LS | 6 Met, 1 SFU, 2 LS | NS |
F = female; M = male; BMI = body mass index; FBG = fasting blood glucose; Met = metformin; SFU = sulfonylurea; LS = lifestyle; Chol = cholesterol (mg/dL × 0.0259 = mmol/L); NS = not significant.