. Author manuscript; available in PMC: 2009 Mar 30.

Published in final edited form as: Arch Neurol. 2008 Jun;65(6):776–785. doi: 10.1001/archneur.65.6.776

Table 2.

Model Estimated Rate of Change of BDS and ADL Scores per Year at Selected Percentiles of Biomarkers

	For BDS Biomarker			For ADL Biomarker
Percentile of Biomarker	Aβ40	Aβ42	Log-hsCRP	Aβ40	Log-hsCRP
1st	5.0	5.0	5.4	11.0	12.0
25th	4.6	4.4	4.6	11.0	10.6
75th	4.0	3.8	3.8	9.4	9.2
99th	3.0	0.6	2.4	4.0	8.0
Change, 25th–75th	0.6	0.6	0.8	1.6	1.4
Change, 1st–99th	2.0	4.4	3.0	7.0	4.0

Abbreviations: Aβ40 and Aβ42, amyloid β-protein 40 and 42, respectively; ADL, Weintraub Activities of Daily Living Scale; BDS, Blessed Dementia Scale; hsCRP, high-sensitivity C-reactive protein.