. Author manuscript; available in PMC: 2010 Feb 1.

Published in final edited form as: Pharm Res. 2008 Oct 9;26(2):480–487. doi: 10.1007/s11095-008-9735-8

Table I.

Effect of curcumin on sulfasalazine, maximal plasma concentration (C_max), T_max and area under concentration-time curve (AUC) in mice.

Curcumin PO Dose (mg/kg)	Cmax (ng/ml)		Tmax (hr)		Interval (hr)	AUC (ng.hr/ml)		Relative exposure AUC_C+SASP/AUC_SASP
Curcumin PO Dose (mg/kg)	SASP	C+SASP	SASP	C+SASP	Interval (hr)	SASP	C+SASP	Relative exposure AUC_C+SASP/AUC_SASP
400	1230	3350	0.5	2	0-4	2170	10380	5.0
					0-24	2170^*	28802	13^*

AUC _{0-24 C + SASP} /AUC_{0-24 SASP}