TABLE 3.
Incidence Rates and Relative Risk (RR) of BCC in TBI Patients Compared to Non-TBI Patients, by Age at HCT
| Age at HCT (years) |
Non-TBI patients (N = 2436) |
TBI patients (N = 3870) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| N | Person-years (PY) |
BCC cases |
Cases per 104 PYa |
N | Person-years (PY) |
BCC cases |
Cases per 104 PYa |
RRb | 95% CIb | P valueb,c | |
| 0–4 | 126 | 861.89 | 0 | 0.0 | 231 | 1434.53 | 3 | 20.9 | 27.7 | 6.16, 88.2 | 0.072 |
| 5–9 | 79 | 726.20 | 0 | 0.0 | 312 | 2353.85 | 11 | 46.7 | 25.8 | 11.1, 56.6 | 0.0099 |
| 10–14 | 90 | 1017.38 | 0 | 0.0 | 281 | 1965.84 | 8 | 40.7 | 11.6 | 4.65, 25.9 | 0.018 |
| 15–19 | 134 | 1251.51 | 1 | 8.0 | 328 | 2483.35 | 20 | 80.5 | 9.17 | 4.98, 16.4 | 0.0017 |
| 20–24 | 113 | 884.17 | 1 | 11.3 | 357 | 2466.40 | 18 | 73.0 | 5.75 | 3.09, 10.4 | 0.0036 |
| 25–29 | 143 | 1143.83 | 4 | 35.0 | 394 | 3048.67 | 26 | 85.3 | 3.63 | 2.17, 5.95 | 0.0024 |
| 30–34 | 186 | 1256.82 | 2 | 15.9 | 454 | 2917.30 | 23 | 78.8 | 2.11 | 1.26, 3.45 | 0.020 |
| 35–39 | 241 | 1379.96 | 7 | 50.7 | 460 | 2762.32 | 29 | 105.0 | 1.88 | 1.19, 2.89 | 0.019 |
| 40–44 | 287 | 1323.36 | 11 | 83.1 | 383 | 2081.60 | 22 | 105.7 | 1.37 | 0.83, 2.16 | 0.13 |
| 45–49 | 313 | 1313.66 | 11 | 83.7 | 334 | 1806.04 | 25 | 138.4 | 1.21 | 0.75, 1.86 | 0.23 |
| 50–54 | 288 | 1101.05 | 14 | 127.2 | 200 | 810.35 | 10 | 123.4 | 0.91 | 0.44, 1.68 | 0.62 |
| 55–59 | 270 | 863.58 | 17 | 196.9 | 109 | 443.77 | 5 | 112.7 | 0.71 | 0.24, 1.64 | 0.81 |
| 60–65 | 166 | 300.42 | 12 | 399.4 | 27 | 63.95 | 2 | 312.7 | 1.81 | 0.29, 6.17 | 0.27 |
a
Crude rate, calculated as 104 × (BCC Cases)/PY.
b
Relative risk (RR) of BCC for TBI patients, compared to non-TBI patients, and 95% confidence interval (CI) for RR estimated from ERR model as described in text.
c
One-tailed P value for testing RR = 1 versus RR > 1.