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Average serum levels of ovarian hormones over the course of the study. Levels of estradiol are shown for placebo monkeys and for monkeys receiving estradiol implants and monthly injections of estradiol. Estradiol levels were greater in monkeys receiving therapy than placebo monkeys. Average levels of progesterone are shown for those monkeys receiving oral doses of prometrium in 12 day blocks each month over the course of the study. E2, estradiol. Bars = SEM.
