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Cerebral cortical cultures were pre-incubated (32 h) with acetaminophen (0–300 μM) (APAP) and oxidatively stressed with menadione (5 μM for 4 h). Chemokines (a) MIP-1α and (b) RANTES released into the supernatant were determined by indirect ELISA. Data are mean ± SD from 3 separate experiments. #p < 0.001 vs. control; **p < 0.01 vs. menadione alone; ***p < 0.001 vs. menadione alone.
