Table 2.

Median (range) doses of artesunate and amodiaquine, expressed as mg/kg, administered on Day 0

	AS/AQ (fixed) N = 373		AS+AQ (loose) N = 375
Age*	AS median (range)	AQ median (range)	AS median (range)	AQ median (range)
0–11 months	3.57 (2.50 – 5.56) N = 54	9.64 (6.75 – 15.00) N = 54	3.57 (2.50 – 6.85) N = 59	10.86 (7.60 – 20.96) N = 59
12+ months	4.67 (1.79 – 10.00) N = 319†	12.62 (4.82 – 27.00) N = 319†	4.72 (2.50 – 10.00) N = 316	14.44 (7.65 – 30.60) N = 316

* Median doses for AS and AQ were significantly (p < 0.0001) higher comparing children <12 vs. ≥ 12 months.

† The weights of 2 patients (19 months old and 42 months old) assigned to the AS/AQ treatment group were not available. Both patients received 2 tablets at 25/67.5 mg each on D0