Moderately differentiated human colorectal adenocarcinomas expressed high levels of C2-O-sLex. (A) A graph of the number of neoplastic cells in well, moderately, and poorly differentiated colorectal adenocarcinomas that were positive for expression of CHO-131 mAb at low (0+ to 1+ staining intensity) and high (2+ to 3+ staining intensity) levels. (B) A graph of the percentage of colorectal adenocarcinomas that were highly positive for C2-O-sLex compared to sLex; n = 22, n = 83, and n = 8 for well, moderately, and poorly differentiated colorectal adenocarcinomas stained with CHO-131 mAb that detected C2-O-sLex; n = 11, n = 112, and n = 11 for well, moderately, and poorly differentiated colorectal adenocarcinomas stained with CSLEX1 mAb that detected sLex. *Moderately differentiated colorectal adenocarcinomas expressed significantly higher levels of C2-O-sLex than well differentiated carcinomas by the Pearson's chi-squared test, p = 0.04.