Table 3.
C2-O-sLex was compared to sLex expression in primary colorectal adenocarcinomas and metastatic liver tumors.
| Differentiation Status | ||||||
|---|---|---|---|---|---|---|
| Well differentiated | Moderately differentiated | Poorly differentiated | ||||
| Antibody staining reactivity in colorectal adenocarcinomas | 0+ | (NE) | 0+ | (1+)* | NE | (NE) |
| 1+ | (2+)* | 1+ | (1+) | 1+ | (3+)* | |
| 2+ | (2+) | 2+ | (3+)* | 2+ | (3+)* | |
| 3+ | (3+) | 3+ | (3+) | 3+ | (3+) | |
| Antibody staining reactivity in metastatic liver tumors | NE | (NE) | 0+ | (0+) | NE | (NE) |
| NE | (NE) | 1+ | (2+)* | NE | (NE) | |
| 2+ | (2+) | 2+ | (2+) | 2+ | (3+)* | |
| 3+ | (2+) | 3+ | (3+) | 3+ | (3+) | |
Serial sections of individual tissues were stained with CHO-131 mAb that detects C2-O-sLex and CSLEX1 mAb that detects sLex. The numbers in the body of the table indicate the intensity of reactivity of a representative single tissue with CHO-131 mAb. The bracketed numbers indicate the intensity of reactivity of a serial section of the same tissue with CSLEX1 mAb. NE = not examined. * indicates a difference in reactivity between CHO-131 and CSLEX1 mAbs.