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. 2009 Apr 10;5(4):e1000372. doi: 10.1371/journal.ppat.1000372

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(A) CD4⁺ T cell subsets of PBMC, PLN, and spleen of macaques H723 and H718 are shown as representatives of ND and MD macaques, respectively. Naive (CD95^lowCD28^high) and memory (CD95^highCD28^high and CD95^highCD28^low) subsets of CD4⁺ T cells were analyzed by flow cytometry. (B) CD4⁺ T cell percentages and their subsets in various tissues from macaques, H723 (upper) and H718 (lower). Naive (blue) and memory (red) CD4⁺ T cells in total T cells are shown. (C) Kinetics of CD4⁺ T cell depletion in H723 (upper) and H718 (lower). Naive (blue dotted line), memory (red), and total (green) CD4⁺ T cell counts in blood are shown.