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. 2008 Apr;22(4):376–380. doi: 10.1155/2008/725702

TABLE 3.

Comparison of dose reductions, discontinuations and hepatitis C virus treatment outcomes between controls and oral cannabinoid-containing medication (OC) recipients

No OC prescribed, % (n/total) OC recipients, % (n/total) P
Patients requiring interferon dose reductions 5 (8/166) 8 (2/25) NS
Patients requiring ribavirin dose reductions 10 (17/166) 8 (2/25) NS
At least 12 weeks of therapy completed* 89 (118/132) 94 (17/18) NS
Full duration of therapy completed* 49 (65/132) 78 (14/18) P=0.02
Sustained virological response achieved 52 (53/101) 79 (11/14) P=0.07

Significance was defined as P<0.05.

*

Patients still on therapy at the time of data censorship were not included in this analysis (n=34 in the non-OC group and n=7 in OC recipients);

The full duration of therapy was 48 weeks for genotypes 1 and 4, and 24 weeks for genotypes 2 and 3;

Patients who did not yet reach the six months after completion of therapy point at the time of analysis have been excluded. NS Not significant