TABLE 1.
CLINICAL CHARACTERISTICS OF HYDROSTATIC PATIENTS AND PATIENTS WITH ACUTE LUNG INJURY WITH PULMONARY EDEMA AND HEALTHY VOLUNTEERS
| HYDRO | ALI/ARDS | Healthy Volunteers | p Value | |
|---|---|---|---|---|
| No. patients | 11 | 22 | 11 | |
| Male sex | 55% | 59% | 55% | NS |
| Smoker | 13% | 35% | 0% | NS |
| Sepsis | 0% | 50% | 0.005 | |
| Age, yr | 45 ± 21 | 42 ± 14 | 35 ± 8 | NS |
| Lung injury score | 2.5 ± 0.7 | 3.1 ± 0.5 | 0.039 | |
| PaO2/FiO2 ratio | 143 ± 90 | 74 ± 27 | 0.002 | |
| Arterial-alveolar gradient, mm Hg | 434 ± 174 | 525 ± 130 | NS | |
| Vt, ml/kg | 9.7 ± 2.1 | 8.2 ± 2.6 | NS | |
| SAPS II score | 37 ± 20 | 49 ± 17 | NS | |
| Ventilator-free days | 19 ± 9 | 7 ± 10 | 0.002 | |
| Hospital mortality | 18% | 68% | 0.01 |
Definition of abbreviations: ALI/ARDS = acute lung injury/acute respiratory distress syndrome; HYDRO = hydrostatic pulmonary edema; NS = statistically not significant; SAPS II = Simplified Acute Physiology Score (44).