TABLE 1.
Characteristics | Group 1* (n = 22) | Group 2 (n = 15) | Group 3 (n = 9) | p Value |
---|---|---|---|---|
Age, yr | 65.3 ± 1.7† | 54.9 ± 2.5 | 43.3 ± 1.7 | < 0.01‡§‖ |
Sex, M/F | 17/5 | 9/6 | 5/4 | |
Pack-years smoking | 68.9 ± 6.9 | 32.7 ± 2.2 | 0.3 ± 0.3 | < 0.0001‡§‖ |
FEV1, L | 1.83 ± 0.13 | 2.66 ± 0.10 | 3.13 ± 0.28 | < 0.0001‡§ |
FEV1, % predicted | 58.55 ± 4.44 | 88.47 ± 3.42 | 99.22 ± 11.87 | < 0.0001‡§ |
FVC, L | 3.35 ± 0.19 | 3.50 ± 0.13 | 3.92 ± 0.33 | 0.21 |
FVC, % predicted | 84.68 ± 4.43 | 94.67 ± 3.69 | 104.0 ± 6.55 | 0.03¶ |
FEV1/FVC | 53.91 ± 2.49 | 76.07 ± 1.26 | 79.77 ± 1.554 | < 0.0001‡§ |
Group 1, chronic obstructive pulmonary disease; Group 2, exsmokers; Group 3, nonsmokers.
Values are given as mean ± SEM unless otherwise noted.
p < 0.005, Group 1 versus Group 2.
p < 0.005, Group 1 versus Group 3.
p < 0.005, Group 2 versus Group 3.
p < 0.05, Group 1 versus Group 3.
Data analysis is by ANOVA and by post hoc analysis with Fisher's protected least significant difference.