Figure 4.

Detection of cathepsins (cat) in BALF. Immunoblot analysis for cat B, L, and S, and cystatin (cys) B and C were performed on baboon necropsy lavage fluids of 140-d, ND, and BPD group baboons. Results are representative of at least two experiments using samples from a total of 6–10 different study animals/group. Black and white arrows indicate procathepsins and mature cathepsins, respectively. The total amount of protein loaded per lane is 4 μg for cat B and cys B and C, and 7 μg for cat L and S immunoblots. *p < 0.05 versus 140 d; ^¶p < 0.05 versus ND.