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. 2006 Mar 23;173(12):1342–1347. doi: 10.1164/rccm.200509-1485OC

Figure 5.

Figure 5.

Proinflammatory cytokine expression. (A, B) IL-1β, IL-6, and IL-8 mRNAs in spleen and liver were increased in control lambs after intratracheal LPS instillation. Proinflammatory cytokine mRNAs in spleen and liver were decreased by rhSP-D. (C) Endotracheal LPS increased IL-1β, Il-6, and IL-8 mRNAs in the lung. Expression of IL-1β was decreased in the group treated with rhSP-D. (D) IL-8 concentrations in plasma were increased in the control group. Plasma IL-8 concentrations were kept low by rhSP-D treatment. *p < 0.05 versus control.