Figure 5.
Mucus production and subepithelial collagen in BALB/c lung tissue obtained 48 h after the last challenge. Sections were stained with PAS (A–D; original magnification: ×100, insets, ×400), Sirius red (E–H), and anti–α-smooth muscle actin (I–L; original magnification, ×400). Representative histology from controls (A, E, and I), short-term challenged mice (sensitized mice exposed to 3 OVA challenges; B, F, and J), and long-term challenged mice (sensitized mice exposed to 7 OVA challenges [C, G, and K] and sensitized mice exposed to 11 OVA challenges [D, H, and L]).