Figure 9.
Changes in airway resistance (RL) in response to inhaled MCh (A) and BAL fluid cellular composition (B) after transfer of bone marrow–derived dendritic cells (BMDCs). After 11 challenges, 106 antigen-pulsed BMDCs or PBS was administered to BALB/c mice via the trachea. Six days later, allergen exposure via the airways was performed on 3 consecutive d followed by assessment of airway function and BAL fluid cell analysis 48 h after the last OVA challenge. *p < 0.05 compared with PBS-administered mice (n = 12/group). Eos = eosinophils; Lym = lymphocytes; Mac = macrophages; Neu = neutrophils.