FIG. 2.
In vitro assessment of the interaction between FLC and RAB against the clinical azole-resistant strain CA10 based on the FICI. (A) Checkerboard showing the percentage of growth for each combination and the combination with more than 20% growth (light gray area). The isoeffective combinations, on the basis of which the FICIs were calculated, are shown in bold. Among all the FICIs calculated based on the isoeffective combinations, FICImax was <4, and so FICImin (0.126) was reported as the FICI. The underlined combination is that with the lowest FICI. (B) Corresponding isobologram of the MICs obtained with combinations of FLC and RAB. The isobole is concave, which indicates synergism.