TABLE 2.
Activity of amoxicillin in experimental endocarditis due to E. faecalis JH2-2 and JH2-2 ΔatlA
| Strain | Bacterial counts (log10 CFU/g vegetation) for treatment regimena
|
P value for treated vs controlsd | |
|---|---|---|---|
| Noneb | Amoxicillinc | ||
| JH2-2 | 9.40 ± 0.62 (4) | 7.69 ± 1.32 (8) | 0.012 |
| JH2-2 ΔatlA | 8.34 ± 1.66 (8) | 8.55 ± 0.68 (8) | 0.746 |
a
Data are expressed as means ± standard deviations. Numbers of rabbits are shown in parentheses.
b
Controls at the start of therapy.
c
Intramuscular administration of 50 mg/kg/day for 3 days.
d
Student's t test.