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. 2009 Feb 2;53(4):1353–1361. doi: 10.1128/AAC.01619-08

TABLE 3.

Time-kill analyses for 12 staphylococci

Drug (no. of strains tested) and dose No. of strains showing indicated % of killing at:
3 h
6 h
12 h
24 h
90 99 99.9 90 99 99.9 90 99 99.9 90 99 99.9
BAL0030543 (12 strains)
    4× MIC 4 0 0 12 6 0 12 12 5 12 12 11
    2× MIC 4 0 0 12 6 0 12 12 4 12 12 11
    1× MIC 3 0 0 12 4 0 12 8 3 8 6 6
BAL0030544 (12 strains)
    4× MIC 6 1 0 12 8 2 12 12 9 12 12 11
    2× MIC 5 1 0 12 7 2 12 12 8 11 10 9
    1× MIC 3 1 0 11 7 2 11 8 4 8 6 3
BAL0030545 (12 strains)
    4× MIC 5 0 0 12 7 1 12 12 7 12 11 11
    2× MIC 3 0 0 12 8 2 12 12 6 11 11 10
    1× MIC 3 0 0 10 4 1 10 8 4 9 6 5
Trimethoprim (5 strains)
    4× MIC 3 0 0 5 4 0 5 5 2 5 5 4
    2× MIC 3 0 0 5 3 0 5 5 3 5 5 3
    1× MIC 2 0 0 5 2 0 5 4 3 3 2 2
Vancomycin (11 strains)
    4× MIC 6 1 0 10 6 3 10 9 4 11 10 10
    2× MIC 5 0 0 9 5 2 10 7 3 10 8 7
    1× MIC 5 0 0 8 5 1 8 5 2 8 6 6
Linezolid (11 strains)
    4× MIC 1 0 0 1 0 0 5 0 0 8 2 0
    2× MIC 0 0 0 1 0 0 4 0 0 8 1 0
    1× MIC 0 0 0 0 0 0 2 0 0 2 0 0
Clindamycin (7 strains)
    4× MIC 1 0 0 0 0 0 3 0 0 7 1 0
    2× MIC 0 0 0 0 0 0 3 0 0 7 3 0
    1× MIC 0 0 0 0 0 0 2 0 0 5 0 0
Minocycline (12 strains)
    4× MIC 1 0 0 3 0 0 8 0 0 10 2 0
    2× MIC 1 0 0 3 0 0 4 0 0 7 2 0
    1× MIC 0 0 0 2 0 0 1 0 0 4 0 0
Rifampin (11 strains)
    4× MIC 7 3 1 9 3 2 11 6 1 11 9 5
    2× MIC 5 3 1 9 3 1 9 5 1 10 8 2
    1× MIC 4 0 0 8 1 0 9 2 0 5 3 1