FIG. 2.

Profiles of resistance of strains 5457 and 5674 and strain 5674-derived tac1 and cdr mutants to azole drugs and different compounds with antifungal activity, as determined by microtiter plate liquid assays. (A) FLC resistance. Cells were incubated for 48 h at 30°C in liquid YPD medium with the indicated concentrations of FLC. The data are presented as the relative growth of cells in FLC-containing medium compared to the growth of the same strain in FLC-free medium, which was set at 100%. The data are the mean of three independent experiments performed in duplicate. (B) KTC resistance. (C) ITC resistance. (D) FPZ resistance. (E) R6G resistance. (F) AMB resistance. For panels B to F, the experiments were performed as described for panel A.