TABLE 1.
C. albicans strains used in this study
| Strain | Genotype or phenotype | Parent | Reference |
|---|---|---|---|
| Clinical isolates | |||
| SC5314 | As | 13 | |
| 5457 | As | 30 | |
| 5674 | Ar (CDR1 CDR2 overexpression) | 5457 | 30 |
| SZY31 | tac1Δ::FRT/tac1Δ::FRT | 5674 | 46 |
| 5674 cdr2 mutant derivatives | |||
| STY1 | cdr2AΔ::SAT1-FLP/CDR2B | 5674 | This study |
| STY2 | CDR2A/cdr2BΔ::SAT1-FLP | 5674 | This study |
| STY3 | cdr2AΔ::FRT/CDR2B | STY1 | This study |
| STY4 | CDR2A/cdr2BΔ::FRT | STY2 | This study |
| STY5 | cdr2AΔ::FRT/cdr2BΔ::SAT1-FLP | STY3 | This study |
| STY6 | cdr2AΔ::SAT1-FLP/cdr2BΔ::FRT | STY4 | This study |
| STY7 | cdr2AΔ::FRT/cdr2BΔ::FRT | STY5 | This study |
| STY8 | cdr2AΔ::FRT/cdr2BΔ::FRT | STY6 | This study |
| 5674 cdr1 mutant derivatives | |||
| STY13 | cdr1AΔ::SAT1-FLPa/CDR1B | 5674 | This study |
| STY14 | cdr1AΔ::SAT1-FLPa/CDR1B | 5674 | This study |
| STY37 | CDR1A/cdr1BΔ::SAT1-FLPb | 5674 | This study |
| STY38 | CDR1A/cdr1BΔ::SAT1-FLPb | 5674 | This study |
| STY15 | cdr1AΔ::FRT/CDR1B | STY13 | This study |
| STY16 | cdr1AΔ::FRT/CDR1B | STY14 | This study |
| STY41 | CDR1A/cdr1BΔ::FRT | STY37 | This study |
| STY42 | CDR1A/cdr1BΔ::FRT | STY38 | This study |
| STY17 | cdr1AΔ::FRT/cdr1BΔ::SAT1-FLPb | STY15 | This study |
| STY18 | cdr1AΔ::FRT/cdr1BΔ::SAT1-FLPb | STY16 | This study |
| STY19 | cdr1AΔ::FRT/cdr1BΔ::FRT | STY17 | This study |
| STY20 | cdr1AΔ::FRT/cdr1BΔ::FRT | STY18 | This study |
| 5674 cdr1, cdr2 mutant derivatives | |||
| STY25 | cdr2AΔ::FRT/cdr2BΔ::FRT cdr1AΔ::SAT1-FLPa/CDR1B | STY7 | This study |
| STY26 | cdr2AΔ::FRT/cdr2BΔ::FRT cdr1AΔ::SAT1-FLPa/CDR1B | STY7 | This study |
| STY27 | cdr2AΔ::FRT/cdr2BΔ::FRT cdr1AΔ::FRT/CDR1B | STY25 | This study |
| STY28 | cdr2AΔ::FRT/cdr2BΔ::FRT cdr1AΔ::FRT/CDR1B | STY26 | This study |
| STY29 | cdr2AΔ::FRT/cdr2BΔ::FRT cdr1AΔ::FRT/cdr1BΔ::SAT1-FLPb | STY27 | This study |
| STY30 | cdr2AΔ::FRT/cdr2BΔ::FRT cdr1AΔ::FRT/cdr1BΔ::SAT1-FLPb | STY28 | This study |
| STY31 | cdr2AΔ::FRT/cdr2BΔ::FRT cdr1AΔ::FRT/cdr1BΔ::FRT | STY29 | This study |
| STY32 | cdr2AΔ::FRT/cdr2BΔ::FRT cdr1AΔ::FRT/cdr1BΔ::FRT | STY30 | This study |
| STY45 | CDR2A-SAT1-FLP/cdr2BΔ::FRT cdr1AΔ::FRT/cdr1BΔ::FRT | STY31 | This study |
| STY47 | CDR2A-FRT/cdr2BΔ::FRT cdr1AΔ::FRT/cdr1BΔ::FRT | STY45 | This study |
a
Disruption cassette derived from pCDR1koA.
b
Disruption cassette derived from pCDR1koB.